I love using the ISE to make building your scripts easier and using F5 and F8 keys to help run your scripts. But I need to use the ISE on SharePoint. No problem just add the snap-in. But wait, the snap-in goes away when you close the ISE. No problem just add the SharePoint snap-in to your profile.
http://thecloudengineer.blogspot.com/2011/10/create-ise-enabled-for-sharepoint.html